Quite a few drugs for cancer are developed from non natural substances. Many thousands of natural chemicals were tried and tested before the first chemo drug came along, and Docetaxel was derived from Yew tree sap. Maybe its made in a lab now. Reid, R.T.; Live, D.H.; Faulkner, D.J.; Butler, A. A siderophore from a marine bacterium with an Exceptional ferric ion affinity constant. Nature 1993, 336, 455–458. [ Google Scholar] [ CrossRef] Schwartz, L.; Guais, A.; Israël, M.; Junod, B.; Steyaert, J.M.; Crespi, E.; Baronzio, G.; Abolhassani, M. Tumor regression with a combination of drugs interfering with tumor metabolism: Efficacy of hydroxycitrate, lipoic acid and capsaicin. Investig. New Drugs 2013, 31, 256–264. [ Google Scholar] [ CrossRef] [ PubMed] Lithostat acetohydroxamic acid is a typical SCOT inhibitor used to treat bladder stones. Another inhibitor, Pimozide [ 40, 41], used to treat mental diseases, reduces cancer incidence. Several interesting compounds are highlighted in the work of Lissanti’s group, who describe potential SCOT inhibitors, the Mitoketoscine [ 42], through their structural and binding properties. Selecting the best and least toxic derivative for animal cancer models requires collaboration with pharmaceutical groups.

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Guy Tenenbaum is a youtuber that I’ve been following for the past 10 months but I’ve watched every video that he’s put out over the past 2 years to document his journey. We hypothesize that 2 years of fasting and ketogenic diet therapy metabolically weakened the neoplastic thymic cell component of the thymoma, “setting the stage” for immune activation and extreme energy restriction to destroy the majority of cancer cells during both relapses, while prednisone-induced apoptosis eradicated the remaining lymphocytic component of the thymoma during the second relapse. This case is unique in that a metabolic-based fasting and ketogenic diet intervention was used as the primary management strategy for a metastatic cancer in the absence of surgery, chemotherapy, or radiotherapy, culminating in a near-complete regression. Kashan, A. Biological roles and therapeutic potential of hydroxyl-carboxilic acid receptors. Front. Endocrinol. 2011, 2, 1–12. [ Google Scholar] Apparently some (but not all) cancers can respond quite strongly to glucose lowering. There are a range of strategies that could help to achieve such glucose reduction. For example, even modest overnight fasting helps-- longer fasts could also be tried. For some, even longer fasts could be attempted, though professional medical advice would be necessary at some stage to maintain safety.

I would have to correct the statement of “being cancer free” to being in remission. Since he is 2-3 years into his diagnosis the surgical castration is likely what got him to where he is and my best interpretation is that his particular cancer is very dependent on testosterone at this time.